Ultrasound Evaluation Of Diaphragmatic Functions And Parasternal Intercostal Muscle Thickening Fraction As Predictors Of Successful Weaning From Mechanical Ventilation

Actively RecruitingAge: 18Years +All GendersID07630662Ultrasound Evaluation of Diaphragmatic Functions and Parasternal Intercostal Muscle Thickening Fraction as Predictors of Successful Weaning From Mechanical VentilationLed by Ain Shams University Updated on 2026-06-0577Participants Needed1Research Sites4 weeksTotal DurationOn this pageAI-SummaryBrief TitleWho Can ParticipateAI-ScreeningYour Study JourneyTrial Site LocationsResearch TeamHow is the study designed?Similar TrialsFrequently Asked QuestionsAI-SummaryWhat This Trial Is AboutCritically ill patients on mechanical ventilation often face challenges in breathing once they attempt to stop ventilator support. This study evaluates the use of ultrasound to assess the function of the diaphragm and parasternal intercostal muscles to predict successful weaning from mechanical ventilation. It addresses complications related to prolonged ventilation and the risks of early ventilator removal in intensive care patients. Participants will undergo a spontaneous breathing trial lasting 30 minutes while positioned semi-sitting at about 30 degrees. During and after this trial, ultrasound assessments of the diaphragm and parasternal intercostal muscles will be performed. The diaphragms movement will be measured using a 3.5-MHz ultrasound probe placed on the chest wall to capture muscle function and thickening, helping to understand respiratory muscle performance during weaning. Throughout the study, patients will be closely monitored during the breathing trial and ultrasound assessments, which take approximately 30 to 60 minutes. The main outcome measured is the muscle function assessed by ultrasound. Researchers aim to gather detailed information about respiratory muscle activity to improve prediction of weaning success, with all evaluations conducted under medical supervision in the intensive care setting.CONDITIONSBrief TitleEffectiveness of Diaphragmatic Function and Parasternal Intercostal Muscles Functions as Predictors for Successful Weaning From Mechanical VentilationWho Can ParticipateAge: 18Years +All GendersEligibility CriteriaYou may qualify if you...Adult patients more than 18 years oldPatients on mechanical ventilation for more than 48 hoursYou will not qualify if you...Declining to give written informed consentPresence of diaphragmatic paralysis or injuryAI-ScreeningAI-Powered ScreeningComplete this quick 3-step screening to check your eligibility123First name *Last name *Email Address *Phone Number *+1Gender*ZIP Code *I agree to receive SMS messages from DecenTrialz regarding trial matching, appointment updates, participant updates, and related information. Message frequency varies. Message & data rates may apply. Reply STOP to cancel or HELP for assistance. I also agree to the Terms of Service and Privacy Policy.*Your Study JourneyScreeningDuration - 2 to 4 weeksParticipants are screened for eligibility to participate in the trial.MonitoringDuration - 30 to 60 minutesParticipants who are eligible and on mechanical ventilation are observed during a spontaneous breathing trial while ultrasound assessments of diaphragmatic and parasternal intercostal muscle functions are performed.1 monitoring session (in-person)Trial Site LocationsTotal: 1 location1Ain shams university hospitalsCairo, EgyptActively RecruitingLoading map...Research TeamMMohamed I Ezz eldeinHow is the study designed?Study TypeOBSERVATIONALMaskingN/AAllocationN/AModelN/APrimary PurposeN/ANumber of Arms1Frequently Asked QuestionsHave more questions? Get in touch with our team for quick supportNot the Right Trial for You?Explore thousands of other clinical trials that might be a better match.Sign up to get personalized trial recommendations delivered to your inbox.Already have an account? Log in hereOn this pageAI-SummaryBrief TitleWho Can ParticipateAI-ScreeningYour Study JourneyTrial Site LocationsResearch TeamHow is the study designed?Similar TrialsFrequently Asked QuestionsSponsorsAAin Shams UniversityLead Sponsor